1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity related to bortezomib, a proteasome inhibitor Employed in the procedure of various myeloma. Its synthesis or analyze is very important for ensuring the purity and basic safety of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor in the synthesis of abiraterone acetate, a drug Employed in the remedy of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound within the synthesis of imatinib, a drug that targets unique sorts of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats different cancers like breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates during the synthesis of gemcitabine, an anti-most cancers drug. Their examine is very important for optimizing the output method and making sure large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is utilised to treat breast cancer, and these intermediates are involved with its manufacturing.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist Employed in the remedy of breast most cancers. Numerous intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug effective in dealing with cancers for b-D-Ribofuranose instance ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the procedure of colorectal cancer and smaller mobile lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is involved with the synthesis of adamantane derivatives, that have many apps, including antiviral properties.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for kind 2 diabetes that inhibits the enzyme DPP-four to control blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is linked to the synthesis of assorted gluconic acid derivatives, which are Utilized in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: GeMcitabine Intermediate 8 A precursor inside the synthesis of canagliflozin, a medication employed to manage kind two diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).